Growing Up in Singapore Towards Healthy Outcomes (NCT01174875) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Growing Up in Singapore Towards Healthy Outcomes
Singapore1,247 participantsStarted 2009-06
Plain-language summary
This study aims to examine the role of genetic and epigenetic factors, maternal nutrition, lifestyle, emotional health, and other environmental factors in pregnancy or postpartum period that can influence future maternal risk of metabolic and mental wellness, including body weight changes. The study will recruit women in early pregnancy and later follow their children after birth, tracking both the mother and child until the child reaches at least 20 years of age.
Who can participate
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria of Mother Participants:
* Women 18 years and above
* Pregnant women attending the first visit (\< 14 weeks GA) at the maternity units of KKH and NUH
* Singapore citizens or Singapore Permanent Residents
* Currently resident in mainland Singapore
* Intention to eventually deliver in KKH or NUH
* Intention to reside in Singapore for the next 5 years
* Intention to donate cord, cord blood and placenta
* The fetus should be racially homogenous with both sets of grandparents of the same ethnicity
Exclusion Criteria of Mother Participants:
* Women whose pregnancies end in miscarriages will be excluded
* Pregnant women on chemotherapy
* Exclude women with significant medical conditions e.g. Type 1 diabetes mellitus, psychosis etc.
* Exclude women on certain medications - e.g. psychotropic drugs.
* Mixed marriages will be excluded
Babies born from these mothers will be invited to participate and followed up until the child is at least 20 years of age.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Roles of fetal, developmental and epigenetic factors in pathways to disease