Comparative Safety and Immunogenicity of VAX128A, VAC128B and VAX128C Novel H1N1 Influenza Vaccine in Healthy Adults

Inclusion Criteria: * Healthy male or female aged 18 - 49 years or \>= 65 years * Give written informed consent * Females have a negative urine test for pregnancy before vaccination and use birth control during 28 day study period * Willing to receive the unlicensed (VAX128) vaccine given as an i.m. injection * Willing to provide multiple blood specimens collected by venipuncture Exclusion Criteria: * Chronic illness that would interfere with the subject's participation in the study or interpretation of the study results. * Impaired immune responsiveness * Received drugs effecting the immunity * Received or plan to receive a nonstudy vaccine within 30 days prior to vaccination and during the study, including licensed influenza vaccines. * History of anaphylactic type reaction to injected vaccines. * History of drug abuse in the year prior to screening. * History of Guillain-Barré Syndrome. * Receipt or donation of blood products * Acute disease within 72 hours prior to vaccination * History of heart or lung disease * Has other conditions that might interfere with study objectives.