CompletedNot Applicable

Gender Differences in the Development, Treatment and Prognosis of Coronary Disease: A CALIBER Study

1,758,584 participantsStarted 2010-07

Plain-language summary

The initial manifestation of symptomatic coronary disease can range from angina (or symptoms of angina), unheralded acute coronary syndrome (ACS), or unheralded coronary death. A better understanding of gender differences in initial presentation of coronary disease and the rate and predictors of progression to subsequent stages in coronary disease could help to identify which gender- specific factors might reduce or slow transition to more serious disease states and improve outcomes. The investigators' research focuses on the role primary care management of cardiovascular risk factors plays in gender differences in the progression to subsequent disease states and to mortality.

Who can participate

Age range35 Years – 100 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * as above Exclusion Criteria: * patients with a history of ischaemic heart disease, heart failure, cerebrovascular disease, peripheral arterial disease or congenital coronary anomalies, prior to entry into the cohort * patients with symptoms of chest pain in the 6 months prior to cohort entry * patients \< 35 or \>100 years of age after eligibility for entry to the cohort

What they're measuring

coronary mortality (ICD 10 I20-I25)

Timeframe: up to 15 years from entry into cohort

Trial details

NCT IDNCT01164371

SponsorUniversity College, London

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2012-09

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