Trial of Different Hypothermia Temperatures in Patients Recovered From Out-of-hospital Cardiac Arrest

Inclusion Criteria: * Age \> 18 * Resuscitated patients from a cardiac arrest with first rhythm of ventricular fibrillation or asystole * Witnessed cardiac arrest * Estimated delay between cardiac arrest and advanced resuscitation \< 20 min. * Resuscitation time from first contact to recovery of spontaneous circulation \< 60 min. * Hemodynamic stability (Mean blood pressure \[BP\] \>60 mmHg), with or without inotropic drugs, before randomization * Glasgow coma score \<9 without sedation before randomization Exclusion Criteria: * Pregnant women or suspected pregnancy or fertile women without a negative pregnancy test * Suspected non-cardiac arrest caused coma * Electrical instability (uncontrollable life-threatening arrhythmias) * Hemodynamic instability (Mean BP ≤60 mmHg), refractory to volume infusion or inotropic drugs * Refractory hypoxemia (saturation \<85% with FiO2=100%) * Previous known terminal illness * Active bleeding or known coagulopathy * Opposition from patient's family to enter the study