CompletedNot Applicable

Effects of Docosahexaenoic Acid (DHA) on Cardiovascular Disease on Diabetic Patients

France16 participantsStarted 2010-05

Plain-language summary

Aim: to determine the effects of DHA supplementation: * on the platelet function through their aggregation and the pathway of arachidonic acid metabolism * on redox status on cells and plasma * on inflammation in 16 type 2 diabetic patients in a cross-over study comparing DHA (400 mg/day for 2 weeks) vs Sunflower oil (placebo). Each period is separated by a wash-out period of 6 to 9 weeks.

Who can participate

Age range55 Years – 75 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * woman * Type 2 diabetes * Menopausal or aged between 55 and 75 years old * Recent HbA1c between 6.5-10% * Oral anti-diabetic drugs or insulin therapy * Hypertension or antihypertensive drug Exclusion Criteria: * Tobacco * Excessive drinking * Post-menopausal hormonal treatment * Treatment by acetylsalicylic acid, clopidogrel, gliclazide, ticlopidine, NSAID * Secondary cardiovascular prevention * antioxidant using * Fish intake \>2 times a week * Anemia \<10g/L * Thrombopenia \<110g/L * Creatinine clearance \<30 ml/min and/or proteinuria \>1g/L

What they're measuring

Platelet function induced by collagen

Timeframe: 4 blood sampling in 10 to 13 weeks

Trial details

NCT IDNCT01150292

SponsorHospices Civils de Lyon

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-02

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