CompletedNot Applicable

Role of Cord Blood Hormones and Epinephrine in the Development of Transient Tachypnea of the Newborn

70 participantsStarted 2008-09

Plain-language summary

In this prospective, cross-sectional study, the aim was to investigate the possible role of cord stress hormones; adrenocorticotropic hormone (ACTH), cortisol, epinephrine, sT3, sT4, and thyroid-stimulating hormone (TSH) in the development of Transient Tachypnea of the Newborn (TTN), via their modulatory effect on epithelial sodium channels and Na-K-ATPase.

Who can participate

Age range34 Weeks – 40 Weeks

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Gestation age \> 34 weeks * C/S delivered infants * Parental consent form signed Exclusion Criteria: * Gestation age \< 34 weeks * Maternal conditions that compromised fetal well-being (hypertensive disorder, diabetes, chorioamnionitis) * Intrauterine growth retardation * Congenital malformations * Absence of parental consent

What they're measuring

Stress response at birth, as demonstrated by cord cortisol, adrenocorticotropic hormone, epinephrine, fT3, fT4, and thyroid-stimulating hormone in late preterm and term neonates developing transient tachypnea of the newborn.

Timeframe: postnatal first 24 hours

Trial details

NCT IDNCT01149928

SponsorAnkara University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2009-08

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