CARDINAL Adjustable Annuloplasty Ring System For Treatment of Mitral Regurgitation

Inclusion Criteria: * Patient is a candidate for mitral valve repair. * Patient able and willing to return to the implant center for follow-up visits. * Able and willing to give informed consent and follow protocol procedures. Exclusion Criteria: * Severe organic lesions with retraction of chordate tendineae, severly fibrotic and immobile leaflets, severely deformed subvalvular apparatus. * Evolving endocarditis or active endocarditis in the last 3 months. * Heavily calcified annulus or leaflets. * Congenital malformation with limited valvular tissue * Patient requires mitral valve replacement. * Previously implanted prosthetic mitral valve or annuloplasty ring/band. * Patient requires aortic or pulmonic valve replacement or repair. * Patient is pregnant (urine HCG test result positive) or lactating. * Patient has a major cardiac or non-cardiac disease, which in the investigator's experience produces an unacceptable surgical risk. * Life expectancy of less than twelve months. * Patient is participating in concomitant research studies of investigational products