CompletedNot Applicable

Comparison Between Internal and External Preoperative Biliary Drainage in Periampullary Cancers

South Korea211 participantsStarted 2010-08

Plain-language summary

Preoperative biliary drainage methods include percutaneous transhepatic biliary drainage (PTBD), endoscopic nasobiliary drainage (ENBD), and endoscopic retrograde biliary drainage (ERBD). Endoscopic biliary drainages often induce peritumoral inflammation and it increase difficulties in determining a proper resection margin. The purpose of this study is to compare the clinicopathological outcomes according to the methods of preoperative biliary drainage in periampullary cancers causing obstructive jaundice, and to find out a proper biliary drainage method.

Who can participate

Age range20 Years – 85 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patient who have periampullary tumors causing obstructive jaundice * patient age: ≥20 and ≤85 * resectable state of disease * no history of previous chemotherapy or radiotherapy * patients without uncontrollable severe cardiovascular, respiratory disease * Karnofsky performance scale ≥70 * informed consent Exclusion Criteria: * patients with distant metastasis or locally advanced disease with major vascular invasion * duodenal cancer * biliary drainage before randomization * previous chemotherapy or radiotherapy * uncontrollable active infection except cholangitis * severe comorbid disease (cardiac, pulmonary, cerebrovascular)

What they're measuring

Incidence of Infectious Complications After Biliary Drainage

Timeframe: within 120 days after drainage

Trial details

NCT IDNCT01134276

SponsorSeoul National University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-05

Results submitted2014-04-07

View on ClinicalTrials.gov More Periampullary Cancers With Obstructive Jaundice trials