Enamel Remineralization Potential of Dentifrices in Situ

Inclusion Criteria: * Good general health with (in the opinion of the investigator) no clinically significant and relevant abnormalities of medical or oral health. * No current active caries or periodontal disease that may compromise the study or health of the subject. * All restorations in a good state of repair * Currently wearing a removable mandibular partial denture with sufficient room in the posterior buccal flange area to accomodate two enamel specimens required dimensions 12 x 7 mm. * Willing to have their denture modified to accomodate enamel test specimens * Willing and capable of wearing removable mandibular partial dentures 24 hours per day during the treatment periods. * Salivary flow rate in the range of normal values (unstimulated whole saliva flow rate greater than or equal to 0.2 mL/ minute; gum base stimulated whole saliva flow rate greater than or equal to 0.8 mL/minute. Exclusion Criteria: * Individuals currently taking antibiotics, or who have taken antibiotics within 30 days prior to the first treatment visit. * Current active caries or periodontal disease that may compromise the study or health of the subject.