Functional and Anatomical Magnetic Resonance Imaging (MRI) of Chronic Brain Injury and Hyperbaric Oxygen (HBO2) Study Subjects

Inclusion Criteria: * Subject has had a brain injury \> 12 months * Subject is \>18 years old * Etiology of brain injury: * stroke * carbon monoxide * anoxia * trauma * Must be able to equalize ears, or have tympanostomy tubes * Willingness to complete outcome measures and comply with the research protocols * Commitment to pay the hospital for hyperbaric oxygen * Subject is enrolled in Hyperbaric Oxygen and Chronic Stable Brain Injury study-clinical trials government ID# NCT00830453. Exclusion Criteria: * Glasgow Coma Score \<13 at the time of consent * Poorly controlled seizures * Inability to participate in outcome assessments (eg: blindness, quadraplegia); Claustrophobia * Inability to equalize ears * Inability to protect airway, or requiring frequent suctioning * Tracheostomy * Women of child-bearing potential or currently pregnant * Severe psychiatric disorders * Taking lithium * Degenerative mental disease * Chronic debilitating disease * Heart failure with ejection fraction \<50% or inability to lay supine * Active malignancy, or prior treatment with cisplatin or bleomycin * Current recreational drug use * Consumption of more than the equivalent of 12 beers/week habitually * Prior treatment with hyperbaric oxygen for chronic brain injury within the last year * Implanted device that is a contra-indication to MRI * Inability to travel to Las Vegas, either by car or by air * Serum creatinine greater than the Intermountain Central Lab normal limit * Unwillingne…