CompletedPhase 4

A Pilot Study Exploring Efficacy and Safety of Amlodipine in the Stented Angina Patients

South Korea211 participantsStarted 2011-09

Plain-language summary

1. OBJECTIVES Primary objective to evaluate the difference of the peak oxygen uptake change (VO2 max, mL/kg/min) in amlodipine group against no CCB group at 9 months Secondary objectives To evaluate the change of sublingual nitrate use per day against no CCB group at 1 and 3 months To evaluate the change of biomarkers against no CCB group at 9 months 2. SUBJECTS AND CENTERS 212, stable angina patients with angiographically confirmed significant residual stenosis 10, 3rd-grade, teaching hospitals in Korea

Who can participate

Age range20 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Stable angina patient with angiographically confirmed significant residual stenosis * Stenosis more than 50% in 2 major coronary arteries at least or Stenosis more than 75% in 1 major coronary artery Exclusion Criteria: * No other pulmonary/psychiatry/musculoskeletal disorder limiting CPET * Contraindicated to the CPET (e.g. unstable angina, aortic stenosis, uncontrolled hypertension, uncontrolled asthma, hypoxemia at rest, epilepsy, locomotor disorder, severe hypertension and febrile illness)

What they're measuring

Exercise capacity

Timeframe: 9 months

Trial details

NCT IDNCT01120327

SponsorSeoul National University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-12

View on ClinicalTrials.gov More Coronary Artery Disease trials