Response to Albuterol Delivered Through an Anti-static Valved Holding Chamber During Nocturnal Bronchospasm

Inclusion Criteria: * Age 18-65 years. * Physician diagnosis of asthma. * FEV1 60-80% predicted during the day. * FEV1 increases ≥ 12 % and to ≥ 80% predicted after 2- 4 puffs of albuterol HFA MDI delivered by antistatic VHC. * No smoking in the previous year and \< 10-pack year history. * No history of severe asthma attacks requiring ER visit or hospitalization in the previous three months. Exclusion Criteria: * Patient required a short course of oral steroid in the past 30 days. * Any disease that is inadequately controlled or any medication that would worsen asthma or interact with asthma medications. * History of viral respiratory tract infection in the 3 weeks prior to the screening visit. * Positive pregnancy test.