UnknownNot Applicable

J-Pouch Colorectal Anastomosis or Straight Colorectal Anastomosis in Treating Patients With Rectal Cancer Who Have Undergone Surgery to Remove the Tumor

Italy600 participantsStarted 2009-10

Plain-language summary

RATIONALE: It is not yet known whether a J-pouch colorectal anastomosis is more effective than a straight colorectal anastomosis in treating patients with rectal cancer who have undergone surgery to remove the tumor. PURPOSE: This randomized clinical trial is studying J-pouch colorectal anastomosis to see how well it works compared with straight colorectal anastomosis in treating patients with rectal cancer who have undergone surgery to remove the tumor.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

DISEASE CHARACTERISTICS: * Histologically confirmed rectal adenocarcinoma meeting the following criteria: * Mid and/or low rectal cancer * Tumor site ≤ 11 cm from anal verge * Must have a temporary stoma (ileostomy or colostomy) * Must be scheduled for a total mesorectal excision with a low anterior rectal resection and mechanic colorectal anastomosis that is potentially curative or with a microscopic residual resection (R0-R1) * No locally recurrent disease * No distant metastasis PATIENT CHARACTERISTICS: * Must be able to understand the study PRIOR CONCURRENT THERAPY: * No prior handsewn coloanal anastomosis * No prior colonic resection * No prior surgery for local recurrence

What they're measuring

Major anastomotic leak rate

Trial details

NCT IDNCT01110798

SponsorAzienda Ospedaliera di Padova

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2011-10

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