CompletedNot Applicable

Reducing Pain and Disability After Breast Cancer Surgery

Canada129 participantsStarted 2009-09

Plain-language summary

The purpose of this study is to determine if the combination of thoracic paravertebral block and multimodal analgesia will decrease chronic pain and arm morbidity in patients undergoing breast cancer surgery with lymph node dissection as compared to patients receiving local anesthesia with multimodal analgesia.

Who can participate

Age range18 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with diagnosis of breast cancer * Scheduled for elective modified radical mastectomy, simple mastectomy with SLNB, breast conserving surgery (ie lumpectomy, segmental mastectomy) with ALND or ALND alone (after positive SLNB) Exclusion Criteria: * American Society of Anesthesiologist (ASA) class 4 or 5 * Patients with contraindications to TPVB * Allergy to study medications * Chronic opioid use defined as daily consumption of greater than 20 mg of oral morphine or equivalent for \>7days * Renal insufficiency defined as a creatinine clearance \<40ml/min as calculated using the Cockroft-Gault formula * Preoperative radiation therapy * Inability to achieve normal shoulder range of motion as defined as \<100o of shoulder abduction or flexion

What they're measuring

The Proportion of Individuals Reporting Chronic Postoperative Pain 12 Months Following Breast Cancer Surgery With Lymph Node Dissection.

Timeframe: 1 year

Trial details

NCT IDNCT01089933

SponsorOttawa Hospital Research Institute

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-09

Results submitted2023-01-05

View on ClinicalTrials.gov More Breast Cancer trials