CompletedPhase 1

Sweet Taste Receptors and the Secretion of Glucagon-like Peptide-1 and Peptide YY

Switzerland16 participantsStarted 2009-04

Plain-language summary

The purpose of this study is to determine the functional significance of sweet taste receptors in the secretion of GI satiety peptides by using a specific sweet taste receptor antagonist to block sweet taste perception in the gut.

Who can participate

Age range18 Years – 40 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy subjects * BMI of 19.0-24.5 * Age 18-40 * stable body weight for at least 3 month Exclusion Criteria: * smoking * substance abuse * regular intake of medication * medical or psychiatric illness * gastrointestinal disorders or food allergies

What they're measuring

Gastrointestinal peptide secretion

Timeframe: 2 hours blood sampling

Trial details

NCT IDNCT01088841

SponsorUniversity Hospital, Basel, Switzerland

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2010-01

View on ClinicalTrials.gov More Appetite and General Nutritional Disorders trials