UnknownPhase 3

Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus Placebo

France64 participantsStarted 2010-03

Plain-language summary

Interest of methotrexate in inflammatory rheumatisms was demonstrated since several years. At present time,there is no effective treatment against digital arthritis. The investigators purpose to measure the efficacy of methotrexate on digital arthritis. In this aim, two groups were compared. The first group receive 10mg/week of methotrexate administered in one shot (every Monday for example)during 12 months. The second group receive 10mg/week of placebo according to the same procedure

Who can participate

Age range40 Years – 85 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * hand arthritis * pain over 40/100 * stable treatment since 4 weeks at least with non-steroid analgesic * between 45 et 85 years Exclusion Criteria: * pregnancy or breast feeding women * hyaluronic acid injection within the past 6 months * cortisonic derivated injection within the past 3 months

What they're measuring

pain assessed with EVA

Timeframe: at screening visit, inclusion visit, first month, and every month during one year

Trial details

NCT IDNCT01068405

SponsorCentre Hospitalier Universitaire de Nice

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2012-03

Contact for this trial

Christian H ROUX, PhD

roux.cr@chu-nice.fr

View on ClinicalTrials.gov More Polyarthritis trials