CompletedNot Applicable

The Effects of Fiber on Appetite and Digestion Hormones

United States22 participantsStarted 2008-08-01

Plain-language summary

In this research study, investigators are interested in how certain dietary fibers in the diet affect certain hormones released from your intestine after eating and how these influence your appetite. The study hypothesis is that certain fibers will slow digestion and absorption of nutrients thereby optimizing fullness,reducing food intake and limiting insulin response in pre- and post-menopausal women.

Who can participate

Age range

18 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female * 18 years or older * Unrestrained \[score ≤ 10\] on the Eating Inventory (EI) questionnaire * Pre-menopausal with spontaneous cycle * Post-menopausal ≥ 12 month without menstruation * Body mass index (BMI) of either 25 to 33 kg/m2, inclusive Exclusion Criteria: * Pregnant and lactating * Smoking * Allergies or intolerances to foods consumed in the study * Fasting glucose \> 110 mg/dL * Active modification to diet or exercise patterns to gain or lose weight in previous 60 days * Unstable body weight (fluctuations of ≥ 5 kg in 60 day period) * Excessive exercisers or trained athletes * Taking any medications that would affect appetite or have a current or past (previous 1 year) medical condition that may interfere with any of the outcomes of this study. * Hormonal therapy (ie., estrogen, progesterone)

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

To investigate the effects of viscous polysaccharide fibers on postprandial satiety.

Timeframe: 0, 20, 40, 60, 90, 120, 150, 180, 210, 240 minutes

To investigate the effects of viscous polysaccharide fibers on postprandial meal-associated metabolic response patterns.

Timeframe: 0, 20, 40, 60, 90, 120, 150, 180, 210, 240 minutes

Trial details

NCT IDNCT01050101

SponsorClinical Nutrition Research Center, Illinois Institute of Technology

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2018-12-01

View on ClinicalTrials.gov More Psychological Phenomena and Processes trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

To investigate the effects of viscous polysaccharide fibers on postprandial satiety.

Timeframe: 0, 20, 40, 60, 90, 120, 150, 180, 210, 240 minutes

To investigate the effects of viscous polysaccharide fibers on postprandial meal-associated metabolic response patterns.

Timeframe: 0, 20, 40, 60, 90, 120, 150, 180, 210, 240 minutes