UnknownPhase 3

ThrombElastoGraphic Haemostatic Status and Antiplatelet Therapy After Coronary Artery Bypass Graft Surgery

Denmark250 participantsStarted 2008-11

Plain-language summary

The purpose of this study is to determine whether adding clopidogrel to aspirin after coronary bypass operation (CABG) improves graft patency, in patients that have preoperatively increased platelet activity(hypercoagulable) and therefore greater risk of graft occlusion( thrombosis).

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Elective/subacute multivessel CABG * Isolated CABG procedure, no concomitant surgery * age \> 18 years * Able to give informed consent Exclusion Criteria: * Myocardial infarction \<48h of surgery * Prior CABG surgery within 1 month * Cardiac Shock within 48h of surgery * Atrial fibrillation * Anticoagulation therapy with VKA * ICH/TCI within 30 days * Prior peptic ulcer· Platelet count \< 150 E9 * Ongoing bleeding * Known platelet disease * Allergic to aspirin or clopidogrel * Liver disease with elevated ALAT/ASAT\> 1,5x normal * Creatinine\> 0,120mmol/l * Contrast allergy * Alcohol or narcotics abuse * Pregnancy * Not able to give informed consent * Geographically not available for follow up

What they're measuring

Graft patency at 3 months

Timeframe: 3 months

Trial details

NCT IDNCT01046942

SponsorRigshospitalet, Denmark

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-05

Contact for this trial

Sulman Rafiq, MD

(0045) 35458728 sulman_raf@hotmail.com

View on ClinicalTrials.gov More Graft Patency trials