UnknownPhase 3

ThrombElastoGraphic Haemostatic Status and Antiplatelet Therapy After Coronary Artery Bypass Graft Surgery

Denmark250 participantsStarted 2008-11

Plain-language summary

The purpose of this study is to determine whether adding clopidogrel to aspirin after coronary bypass operation (CABG) improves graft patency, in patients that have preoperatively increased platelet activity(hypercoagulable) and therefore greater risk of graft occlusion( thrombosis).

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Elective/subacute multivessel CABG * Isolated CABG procedure, no concomitant surgery * age \> 18 years * Able to give informed consent Exclusion Criteria: * Myocardial infarction \<48h of surgery * Prior CABG surgery within 1 month * Cardiac Shock within 48h of surgery * Atrial fibrillation * Anticoagulation therapy with VKA * ICH/TCI within 30 days * Prior peptic ulcer· Platelet count \< 150 E9 * Ongoing bleeding * Known platelet disease * Allergic to aspirin or clopidogrel * Liver disease with elevated ALAT/ASAT\> 1,5x normal * Creatinine\> 0,120mmol/l * Contrast allergy * Alcohol or narcotics abuse * Pregnancy * Not able to give informed consent * Geographically not available for follow up

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Graft patency at 3 months

Timeframe: 3 months

Trial details

NCT IDNCT01046942

SponsorRigshospitalet, Denmark

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-05

Contact for this trial

Sulman Rafiq, MD

(0045) 35458728 sulman_raf@hotmail.com

View on ClinicalTrials.gov More Graft Patency trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.