CompletedPhase 1

Sympathetic Neural Outflow During Xenon Anesthesia in Humans

Germany8 participantsStarted 2010-01

Plain-language summary

The purpose of this study is to test the hypothesis that sympathetic neural outflow to muscles as well as a sympathetic baroreflexes are not altered during xenon anesthesia in Healthy Volunteers.

Who can participate

Age range18 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Healthy volunteers \> 18 years and \< 65 years of age * ASA physical status I * Legal competence * for whom the consent form has been signed Exclusion Criteria: * Healthy volunteers \< 18 years and \> 65 years of age * Pregnancy, lactation period or missing secure anticonvulsive therapy * Missing legal competence * Participation in other clinical trials * Contraindications as mentioned on §4.3 of the SPCs of LENOXe™ (xénon 100 % v/v) * Any medication especially of Sildenafil (Viagra®) or other potency remedy * Existing relationship of dependency to the sponsor or the investigator

What they're measuring

Muscle Sympathetic Activity (MSA)and Baroreflex reagibility under Xenon Anesthesia in comparison to awake

Timeframe: 30 minutes

Trial details

NCT IDNCT01043419

SponsorAir Liquide Santé International

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2010-03

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