Tai Chi for Osteopenic Women (NCT01039012) | Clinical Trial Compass
UnknownPhase 2
Tai Chi for Osteopenic Women
United States86 participantsStarted 2008-01
Plain-language summary
This study will assess the effectiveness of Tai Chi to affect the rate of bone loss in post-menopausal women who have been diagnosed with the initial stages of bone thinning.
Who can participate
Age range45 Years – 70 Years
SexFEMALE
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Inclusion Criteria:
* Women ages 45-70 years
* BMD T-scores of the hip (femoral neck or trochanter) and/or spine between -1.0 and -2.5
* Post-menopausal w/out menses for ≥ 12 months
* Sedentary, i.e. do not regularly participate in physical exercise on average 1 or more times per week
Exclusion Criteria:
* Osteoporotic (T-score \< -2.5) or a fracture in the past 2 years not caused by motor vehicle accident
* Prior or current use of use of medication that increase risks of fracture (e.g. steroids, anti-convulsants, anticoagulants, lithium)
* Prior or current use of medications that modify bone metabolism (e.g. bisphosphonates, selective estrogen receptor modulators such as Raloxifene)
* Use of calcium supplements above levels suggested within the recommendations of standard care (i.e., above 1200-1500 mg)
* Current or prior year use of estrogen or calcitonin
* Malignancies other than skin cancer
* Diagnosis of anorexia along with a BMI of \< 17.5
* Conditions that cause secondary osteoporosis (e.g. Cushing's syndrome, Marfan's syndrome)
* Tobacco use in past year
* Physical or mental disabilities that will preclude informed consent or active study participation
* Geographic or scheduling limitations that would preclude required participation in weekly Tai Chi classes and study procedures
* Current regular practice of Tai Chi
What they're measuring
1
Serum markers of bone resorption (CTX, C-terminal cross linking telopeptide of type I collagen), and bone formation (osteocalcin).
Timeframe: Baseline, 3 months, 9 months
2
Bone mass density of the lumbar spine and proximal femur (dual-energy X-ray absorptiometry).