Active — Not RecruitingNot Applicable

Genetic and Environmental Risk Factors Related to Esophageal Cancer

United StatesStarted 2000-04

Plain-language summary

RATIONALE: Gathering information about genes, cigarette smoking, and diet may help doctors learn more about risk factors that may cause esophageal cancer. PURPOSE: This clinical trial is studying genetic and environmental risk factors related to esophageal cancer.

Who can participate

Age range18 Years – 100 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

DISEASE CHARACTERISTICS: * Meets 1 of the following criteria: * Diagnosis of esophageal cancer (patient) * Newly diagnosed disease * Receiving care at Massachusetts General Hospital, Thoracic Oncology Center * Friend or spouse of patient (healthy participants) PATIENT CHARACTERISTICS: * No concurrent psychiatric incapacity or dementia PRIOR CONCURRENT THERAPY: * Not specified

What they're measuring

Polymorphisms in various pathways, DNA repair, free-radical formation, inflammatory genes, metastatic potential, and cell cycle or tumor suppression in blood samples

Timeframe: 2000-2016

Comparison of presence or absence of variant polymorphisms between cases and controls

Timeframe: 2000-2016

Correlation between polymorphisms in blood samples and polymorphisms in tissue specimens

Timeframe: 2000-2016

Analyses of dietary factors and Helicobacter pylori infection (previous vs current)

Timeframe: 2000-2016

Trial details

NCT IDNCT01035398

SponsorMassachusetts General Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-06

View on ClinicalTrials.gov More Esophageal Cancer trials