A Trial to Compare the Efficacy of Two Formulations of Avotermin Against Placebo

Inclusion Criteria: * Males and females aged 18-85 years who have given written informed consent * Subjects with a body mass index within range 18-35 kg/m2 * Subjects with clinically acceptable results for the laboratory tests specified in the trial protocol * Female subjects using a highly effective method (S) of contraception Exclusion Criteria: * Subjects who have a history of keloid scarring, surgery within one year of the first dosing area * Subjects who have current scars, tattoos, birthmarks, mole within 3 cm of the area to be excised * Subjects with any clinically significant medical condition or history of any condition which may impair wound healing