Active — Not RecruitingNot Applicable

Identification of Genetic Causes of Bicuspid Aortic Valve Disease

United States11,000 participantsStarted 2009-12

Plain-language summary

BAVgenetics is a partnership between Investigators at Boston University, Brigham and Women's Hospital, and Massachusetts General Hospital dedicated to discovering the genetic causes of bicuspid aortic valve disease and associated aortic disease.

Who can participate

Age range14 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Any adult patient ≥ 14 years of age may be recruited regardless of gender, ethnicity or racial group. * Patients with a diagnosis of bicuspid aortic valve will be enrolled. * Patients who have had their bicuspid aortic valve previously replaced will also be enrolled. * Relatives of patients with a diagnosis of bicuspid aortic valve are also welcomed to be enrolled regardless if they have BAV or not, as it is helpful to examine the DNA of first degree relatives. Exclusion Criteria: * Non-English speaking

What they're measuring

Identification of genetic variants associated with the occurrence of bicuspid aortic valve disease

Timeframe: 20 years

Trial details

NCT IDNCT01026571

SponsorBoston University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2029-12

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