TerminatedNot Applicable

Timing of Dilation Tracheostomy in Mechanically Ventilated Chronic Obstructive Pulmonary Disease (COPD) Patients

Stopped: unexpectedly slow recruitment

Germany23 participantsStarted 2009-10

Plain-language summary

The purpose of this study is: * to evaluate the optimal time-point for percutaneous dilation tracheostomy in COPD patients in terms of duration on mechanical ventilation, length of stay on ICU and mortality; * to evaluate the rate of infections and infectious complications of tracheostomized COPD patients; * to evaluate the spectrum of pathogens in tracheostomized and intubated COPD patients; * to evaluate the amount of sedatives used in mechanically ventilated COPD patients; * to assess the quality of life in COPD patients tracheostomized after 3 or after 10 days.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosis of COPD (GOLD stage III or IV) * Suspected long-time invasive mechanical ventilation due to ARF (\> 10 days) * Informed consent of the patient or legal guardian Exclusion Criteria: * Severe neurological failure (such as stroke, cerebral haemorrhage etc.) * Immunosuppressant therapy (with the exception of steroid therapy) * Major risk of bleeding * Intubation \> 72 h * Contraindication for dilation tracheotomy * Impossibility of intubation

What they're measuring

Cumulative duration of mechanical ventilation (in days)

Timeframe: Day 1 - 28

Trial details

NCT IDNCT01021202

SponsorUniversitätsklinikum Hamburg-Eppendorf

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-04

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