CompletedPhase 4

Dexmedetomidine Versus Propofol in Vitreoretinal Surgery

United States78 participantsStarted 2009-10

Plain-language summary

The investigators would like to determine if using Dexmedetomidine alone or in a reduced dose can prevent or reduce the incidence of adverse effects, while providing adequate sedation, and respiratory stability as compared to propofol.

Who can participate

Age range18 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * American Society of Anesthesiologists rating of I-III * good renal and liver function Exclusion Criteria: * renal and hepatic insufficiency * uncontrolled diabetes * uncontrolled hypertension * severe cardiac disease Class III or IV * heart blocks * chronic use of sedatives, narcotics, alcohol or illicit drugs * allergy to either propofol or dexmedetomidine * pregnancy or inability to tolerate technique of the study drugs

What they're measuring

Adequate Sedation Via Bispectral Index Score (BIS)and University of Michigan Sedation Scale (UMSS)

Timeframe: Intraoperative up to 120 min

Intraoperative Hemodynamic Stability

Timeframe: Intraoperative up to 120 min

Intraoperative Respiratory Stability

Timeframe: Intraoperative up to 120 min

Intraoperative Heart Rate Stability

Timeframe: Intraoperative up to 120 min

Trial details

NCT IDNCT01001429

SponsorRutgers, The State University of New Jersey

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-03

Results submitted2016-02-11

View on ClinicalTrials.gov More Retinal Detachment trials