Active — Not RecruitingNot Applicable

Intravenous (IV) Saline and Exercise in Postural Tachycardia Syndrome (POTS)

United States40 participantsStarted 2009-10

Plain-language summary

The investigators will test whether an intravenous infusion of saline (salt water) will improve the exercise capacity in patients with postural tachycardia syndrome (POTS).

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Meet diagnostic criteria of Postural Tachycardia Syndrome (POTS) 28 * Age between 18-65 years * Male and female are eligible (although the majority of POTS patients are female). * Able and willing to provide informed consent Exclusion Criteria: * Presence of medical conditions that can explain postural tachycardia (e.g., acute dehydration, medications) * Pregnancy * Other factors which in the investigator's opinion would prevent the subject from completing the protocol. * Patients who are bedridden or chair-ridden

What they're measuring

Difference in VO2max between saline day and placebo day

Timeframe: Within 2 week

Trial details

NCT IDNCT01000350

SponsorVanderbilt University Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-06

View on ClinicalTrials.gov More Postural Tachycardia Syndrome trials