Lifestyle Intervention in Obese Non-diabetic Adults With a Family History of Diabetes. (NCT00993603) | Clinical Trial Compass
CompletedNot Applicable
Lifestyle Intervention in Obese Non-diabetic Adults With a Family History of Diabetes.
United Kingdom66 participantsStarted 2010-09
Plain-language summary
The aim of this study is to investigate weather gradual weight loss achieved with healthy lifestyle changes influence hormonal factors affecting appetite and blood glucose control in obese people without presence of diabetes.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. BMI between 30-39.9kg/m2
. Family history of diabetes (self reported)
. Normal and impaired glucose tolerance
. Obtain informed consent
Exclusion criteria
. BMI less than 30kg/m2 or more than 39.9kg/m2
. Presence of diabetes or any other chronic disease or disability that might interfere with the study results
. Anti-obesity or any other prescription medications that may interfere with the study results
. Pregnancy
. Unable to converse competently in English as special arrangements would need to be made for such people and this would be impractical in a group setting
. Attending another weight management programme
. Patients who would be unable to attend at least 75% of the programme sessions for medical or other reasons
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
To estimate the correlation between weight loss over 8 months achieved through a programme of intensive lifestyle management and changes in GLP-1 production over the same period in obese without presence of diabetes but with family history of diabetes.