Evaluation of Trinity Evolution in Patients Undergoing Foot and Ankle Fusion

Inclusion Criteria: * Foot and/or ankle pathology requiring fusion using open surgical technique with supplemental bone graft/substitute requiring one of the following procedures: * Ankle joint fusion * Subtalar fusion * Calcaneocuboid fusion * Talonavicular fusion * Double fusions (talonavicular and calcaneocuboid joints) * Triple fusions (subtalar, talonavicular, and calcaneocuboid joints) * At least 18 years of age * Willing and able to comply with the requirements of the protocol including follow-up requirements * Willing and able to sign a study-specific informed consent. Exclusion Criteria: * Use of any other bone graft or bone graft substitute in addition to or in place of Trinity Evolution at the time of surgery * Use of adjunctive post-operative stimulation * Active local or systemic infection * Currently pregnant or considering becoming pregnant during the follow-up period * Active malignancy or having been on chemotherapy of any kind for a malignancy in the past 1 year * Immunosuppressive therapy of any kind within the past 1 year * Has a known history of hypersensitivity or anaphylactic reaction to dimethyl sulfoxide (DMSO).