Safety Study of Seasonal Influenza Vaccine by Jet Injection

Inclusion Criteria: * Age 18 and 49 years, inclusive * In good health as evidenced by screening evaluation within the 30 days prior to immunization. * Expressed interest and availability to fulfill the study requirements. * Signed, informed consent. * For women of child-bearing potential, agreement to avoid pregnancy for the 90 days following vaccination by use of effective birth control methods. * Agreement to refrain from taking any experimental drug or vaccine from Day minus 30 to Day 90 (from screening until the volunteer completes the study). Exclusion Criteria: * A known allergy to a component of the vaccine, including egg, egg products, chicken proteins, formaldehyde, gentamicin sulfate, or sodium deoxycholate. * A positive urine pregnancy test in the 24 hours prior to vaccination. (A negative urine pregnancy test is required within the 24 before vaccination for all women who have not had a hysterectomy or are not at least 1 year post-menopausal) * A woman who is breastfeeding. * Any current medical illness that might jeopardize the volunteer's safety or interfere with the interpretation of the study results. These include, but are not limited to the following: cancer; immunodeficiency; bleeding disorder. * Any underlying medical condition for which influenza vaccination is recommended: chronic heart or lung conditions, including asthma; metabolic diseases; kidney disease; blood disorder (such as sickle cell anemia); weakened immune systems, including HIV/AIDS. * Re…