CompletedNot Applicable

MRI Mapping in Planning Radiation Therapy to the Base of Skull and Brain in Patients With Nonmetastatic Head and Neck Cancer

United States3 participantsStarted 2008-10

Plain-language summary

RATIONALE: Diagnostic procedures, such as specialized types of magnetic resonance imaging (MRI), may help in planning radiation therapy that does less damage to normal tissues. PURPOSE: This phase I trial is studying using functional MRI to see how well it works in planning radiation therapy in patients undergoing radiation therapy to the base of the skull and/or brain for nonmetastatic head and neck cancer.

Who can participate

Age range18 Years – 120 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

DISEASE CHARACTERISTICS: * Histologically confirmed head and neck cancer that requires radiotherapy to the base of the skull * No evidence of metastatic disease PATIENT CHARACTERISTICS: * ECOG performance status 0-1 * Life expectancy ≥ 1 year * Not pregnant * Negative pregnancy test * Able to undergo standard CT simulation and radiotherapy treatment planning and delivery, including the capacity to comply with standard immobilization devices to the head and neck for daily irradiation * Able to undergo standard MRI and deemed capable of complying with the immobilization needs and tasks required for functional MRIs * No claustrophobia * No patients with pacemakers, metal fragments in the eye, or certain metallic implants PRIOR CONCURRENT THERAPY: * Not specified

What they're measuring

Feasability, as assessed by the proportion of study patients with functional regions identified within the brain as receiving exit irradiation

Timeframe: 90 days

Trial details

NCT IDNCT00984074

SponsorAbramson Cancer Center at Penn Medicine

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2011-12

View on ClinicalTrials.gov More Head and Neck Cancer trials