CompletedNot Applicable

Study of Blood and Tissue Samples From Patients With Aggressive Non-Hodgkin B-Cell Lymphoma or Hodgkin Lymphoma

United States52 participantsStarted 2009-08

Plain-language summary

RATIONALE: Studying samples of blood and tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research study is looking at blood and tissue samples from patients with aggressive non-Hodgkin B-cell lymphoma or Hodgkin lymphoma.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

DISEASE CHARACTERISTICS: * Diagnosis of an untreated aggressive B-cell lymphoma, including: * Diffuse large B cell/immunoblastic lymphoma * Burkitt lymphoma * Hodgkin lymphoma * Serological documentation of HIV infection by any of the FDA-approved tests * Available diagnostic material from fresh frozen tissue or formalin-fixed paraffin embedded tissue OR willing to undergo a repeat biopsy (fine needle aspiration is acceptable) PATIENT CHARACTERISTICS: * Not specified PRIOR CONCURRENT THERAPY: * Not specified

What they're measuring

Proportion of patients with diffuse large B-cell/immunoblastic and Burkitt histologies with elevated serum free light chains (FLC)

Timeframe: Study entry

Proportion of patients with Hodgkin lymphoma clonal immunoglobulin (Ig) DNA detection in the plasma

Timeframe: Study entry

Trial details

NCT IDNCT00981097

SponsorAIDS Malignancy Consortium

Sponsor typeNETWORK

Study typeOBSERVATIONAL

Primary completion2013-06

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