UnknownPhase 4

Endoscopic Band Ligation (EBL) Versus Endoscopic Band Ligation and Propranolol for the Prevention of Variceal Rebleeding

South Korea180 participantsStarted 2008-08

Plain-language summary

Both propranolol and endoscopic band ligation (EBL) are effective for prevention of variceal rebleeding. Recently several studies compared the efficacy of EBL alone and with a combination of propranolol and EBL. However, the results of recent studies showed discrepancy. This study is performed to compare the efficacy and safety of EBL alone and EBL combined with propranolol in patients without previous history of endoscopic variceal treatment.

Who can participate

Age range18 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * liver cirrhosis * age between 18 and 70 years * Successful control of esophageal variceal bleeding within 6 weeks before enrollment Exclusion Criteria: * Gastric variceal bleeding * Patients with systolic blood pressure \<100 mmHg or basal heart rate \<60/min * Portal vein thrombosis * Prominent hepatic encephalopathy * Coexisting untreated malignancy * Severe cerebrovascular or cardiovascular disease, renal failure * Previous history of endoscopic, radiologic, or surgical treatment for varices or ascites * Contraindication to beta-blocker * Pregnancy * Refusal to give consent to participate in the trial

What they're measuring

Rebleeding from esophageal varices

Timeframe: 2 years

Trial details

NCT IDNCT00966121

SponsorKorea University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-07

Contact for this trial

Soon Ho Um, Prof

82-2-920-5019 umsh@korea.ac.kr

View on ClinicalTrials.gov More Cirrhosis trials