WithdrawnNot Applicable

Breathing Device for Orthostatic Hypotension (OH)

Stopped: No volunteers were enrolled, study was closed

United States0Started 2010-12

Plain-language summary

The investigators will test whether breathing through an inspiratory resistance device will improve the ability to be upright and decrease blood pressure drops on standing in patients with orthostatic hypotension.

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosed with neurogenic orthostatic hypotension by the Vanderbilt Autonomic Dysfunction Center * Decrease in systolic blood pressure ≥ 20 mmHg with position change from supine to standing (10 minutes) * Evidence of reproducibility suggestive of non-reversible nervous system origin for the orthostatic hypotension * Age between 18-80 years * Male and female subjects are eligible * Able and willing to provide informed consent Exclusion Criteria: * Overt cause for orthostatic hypotension (such as acute dehydration) * Inability to give, or withdrawal of, informed consent * Pregnant * Other factors which in the investigator's opinion would prevent the subject from completing the protocol

What they're measuring

Magnitude of drop in Systolic Blood Pressure during head-up tilt

Timeframe: 1 min

Trial details

NCT IDNCT00962884

SponsorAlfredo Gamboa

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-12

View on ClinicalTrials.gov More Orthostatic Hypotension trials