Active — Not RecruitingNot Applicable

Breathing Device in Postural Orthostatic Tachycardia Syndrome (POTS)

United States30 participantsStarted 2009-07

Plain-language summary

The investigators will test whether breathing through an inspiratory resistance device will improve the ability to be upright and decrease heart rate increases on standing in patients with postural tachycardia syndrome.

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosed with postural tachycardia syndrome by the Vanderbilt Autonomic Dysfunction Center * Increase in heart rate ≥ 30 beats/min with position change from supine to standing (10 minutes) * Chronic symptoms consistent with POTS that are worse when upright and get better with recumbence * Able and willing to provide informed consent Exclusion Criteria: * Overt cause for postural tachycardia (such as acute dehydration) * Inability to give, or withdrawal of, informed consent * Pregnant * Other factors which in the investigator's opinion would prevent the subject from completing the protocol

What they're measuring

Magnitude of orthostatic heart rate increase on upright posture

Timeframe: 10 min

Trial details

NCT IDNCT00962728

SponsorAlfredo Gamboa

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-11

View on ClinicalTrials.gov More Postural Tachycardia Syndrome trials