CompletedNot Applicable

Effects of Nocturnal Non-invasive Ventilation in Patients With Amyotrophic Lateral Sclerosis

Taiwan70 participantsStarted 2009-01

Plain-language summary

Specific aims: Aim 1. To determine the incidence of hypoventilation in Amyotrophic Lateral Sclerosis (ALS) patients. Aim 2. To identify the clinical characteristics and risk factors associated . Aim 3. To determine the effect of early intervention with nocturnal NIV on the prognosis of ALS patients.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * ALS patients who: * had FVC 40%-80% of predict * Pimax \< 60 mmHg * daytime PaCO2 \< 50 mmHg Exclusion Criteria: * Refuse to participate * Require mechanical ventilation * Active neurologic event other than ALS * Obstructive pulmonary disease * Active infection * Need sedatives or narcotics within 3 days of sleep study * Participating in other study at the same time

What they're measuring

Survival

Timeframe: 36 months

Trial details

NCT IDNCT00958048

SponsorNational Taiwan University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-04

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