* To assess whether acute, moderate Champagne wine consumption modulates endothelial function in healthy human volunteers. * To establish the bioavailability of Champagne wine polyphenols and their metabolism.
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Assessment of endothelial function by Laser Doppler Imaging with iontophoresis. Blood Assessment of lipid profile, inflammatory markers, plasma antioxidant and oxidant capacity, liver enzyme and metalloproteinase blood concentrations.
Timeframe: 6 months