Sleep Deprivation and Energy Balance (NCT00935402) | Clinical Trial Compass
CompletedNot Applicable
Sleep Deprivation and Energy Balance
United States30 participantsStarted 2008-11
Plain-language summary
Observational and epidemiological studies have found a link between obesity and short sleep duration with the prevalence of both increasing in the past decades. At this time, it is unknown whether short sleep is a cause of obesity and how short sleep would lead to obesity. Some studies associate short sleep with increased levels of hormone that stimulate appetite. This study will examine how food intake and energy expenditure can be modified by sleep duration as a means of understanding a potential causal pathway.
Who can participate
Age range
30 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Body mass index 22-25 kg/m2
* Right-handed
* Sleep 7-9 hours/night
* Normal score on Pittsburgh Quality of Sleep questionnaire, Epworth Sleepiness Scale, Berlin Questionnaire, Sleep Disorders Inventory Questionnaire, Beck Depression Inventory, Composite Scale of Morningness/Eveningness
Exclusion Criteria:
* Smoker
* Neurological, medical, or psychiatric disorder
* Diabetics
* History of eating disorders
* Sleep disorders
* Travel across time zones within 4 weeks of the study
* History of drug and alcohol abuse
* Shift worker
* Caffeine intake \> 300 mg/d
* Excessive daytime sleepiness
* Regular napping
* History of drowsy driving
* Pregnancy or within 1 y post-partum
* Heavy equipment operator or commercial long-distance driver
* Contra-indications for MRI scanning
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Resting metabolic rate
Timeframe: Day 5 of each arm
2
Food intake
Timeframe: Days 5-6 of each arm
3
Hormone Measurements
Timeframe: Daily fasting, and every 2 hours on day 4 of each arm