CompletedPhase 3

Reduction of Cesareans by Nitric Oxide (NO) Donors in Post Term Pregnancies

France1,409 participantsStarted 2009-06

Plain-language summary

The purpose of this trial is to determine whether cervical ripening with isosorbide mononitrate reduce caesarean section in women with post term pregnancies.

Who can participate

Age range18 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria : * Age \> or = 18 years old * TAS \> or = 95 mmHg * Singleton * Nulliparity * Term \> or = 41 weeks + 0 day * Bishop score \< or = 5 * Vertex presentation * Intact membranes * No contra-indications of the study treatment * No maternal or fetal diseases which could indicate immediate labor induction * Written informed consent Exclusion criteria : * Multiple pregnancy * Multiparity * Term \< 41 weeks * Bishop score \> 5 * Breech presentation * Rupture of the membranes * Previous cesarean * Indication to immediate labor induction * Contraindications to isosorbide mononitrate * No co-administration of antihypertensive drugs * No social security

What they're measuring

Number of cesarean sections

Timeframe: 10 days

Trial details

NCT IDNCT00930618

SponsorAssistance Publique - Hôpitaux de Paris

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-12

View on ClinicalTrials.gov More Prolonged Pregnancy trials