CompletedNot Applicable

Metabolic Syndrome in Childhood Cancer Survivors

United States512 participantsStarted 2005-04

Plain-language summary

RATIONALE: Gathering information about how often metabolic syndrome occurs in young survivors of childhood cancer may help doctors learn more about the disease. PURPOSE: This clinical trial is studying metabolic syndrome in survivors of childhood cancer and in their healthy sisters and brothers.

Who can participate

Age range

9 Years – 18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Subjects must be survivors of childhood cancer, treated at Fairview-University Medical Center or Children's Hospitals and Clinics of Minneapolis and St Paul or siblings of survivors. * Subjects will be 9-17 years old at the time of their visit. * Subjects who are cancer survivors must have survived childhood cancer for a minimum of 5 years and be in remission. Exclusion Criteria: * Eligibility will not be restricted by race or sex. * Any women currently pregnant will not be eligible, but may participate 3 or more months after the end of her pregnancy if the study is still ongoing. * Subjects who underwent hematopoietic cell transplant (HCT) are not eligible for this study.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Metabolic syndrome (MS) in survivors of childhood cancer (CCS) vs controls

Timeframe: Day 1 and Day 2

Insulin resistance (IR) in CCS vs controls

Timeframe: Day 1 and Day 2

Correlation of obesity and IR to other factors associated with the development of the MS that may be altered in the CCS

Timeframe: Day 1 and Day 2

Dietary and a physical activity assessments of CCS vs controls

Timeframe: Day 1 and Day 2

Trial details

NCT IDNCT00920738

SponsorUniversity of Minnesota

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2010-07

View on ClinicalTrials.gov More Brain and Central Nervous System Tumors trials

Who can participate

Age range

9 Years – 18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Metabolic syndrome (MS) in survivors of childhood cancer (CCS) vs controls

Timeframe: Day 1 and Day 2

Insulin resistance (IR) in CCS vs controls

Timeframe: Day 1 and Day 2

Correlation of obesity and IR to other factors associated with the development of the MS that may be altered in the CCS

Timeframe: Day 1 and Day 2

Dietary and a physical activity assessments of CCS vs controls

Timeframe: Day 1 and Day 2