Trial Assessing the Efficacy of a Short Course of Intravenous Antibiotic Followed by Oral Antibiotic in Uncomplicated Acute Diverticulitis

Inclusion Criteria: * clinical diagnosis of uncomplicated acute diverticulitis confirmed by a computed tomography (CT) scan within 24-48 hours Exclusion Criteria (prerandomization): * immunocompromised patients * pregnant women * clinical suspicion or CT confirmation of complicated acute diverticulitis * Karnofsky performance score less than 50% * allergy to penicillin Exclusion Criteria (postrandomization): * withdrawal of the trial * CT confirmation of complicated acute diverticulitis * CT not conforming to acute diverticulitis * CT performed 72 hours after the admission * adverse reaction to the antibiotic * bacteriemia