Efficacy of Pregabalin in Patients With Radicular Pain (NCT00908375) | Clinical Trial Compass
CompletedPhase 4
Efficacy of Pregabalin in Patients With Radicular Pain
United States39 participantsStarted 2009-05
Plain-language summary
The purpose of this study is to evaluate whether pregabalin is effective in reducing the pain in patients who present with radicular pain due to a herniated disc, spinal stenosis or failed back surgery syndrome.
Who can participate
Age range18 Years – 64 Years
SexALL
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Inclusion criteria
✓. Patients with pain in dermatomal distribution, in either cervical or lumbar region.
✓. History of pain for more than 3 months.
✓. History of herniated disc, spinal stenosis or failed back surgery.
✓. A series of epidural steroid injections within the past 6 months.
✓. Presence of motor or sensory neurological signs (hypoesthesia, hyperesthesia, allodynia, dysesthesia) in the affected dermatomes.
✓. Patients must be cognitively capable of completing the pain questionnaires.
Exclusion criteria
✕. Patients below 18 or over 65 years of age.
✕. Patients with mostly axial spinal pain.
✕. Presence of significant motor deficits, and /or bowel and/or bladder dysfunction.
✕. Workmen's compensation or disability issues.
✕. Patients with chronic depression and on depression medications.
✕. Addiction and/or substance abuse issues.
✕. Patients using gabapentin or failure to respond to previous gabapentin use.