Biomarkers in Patients With Kidney Cancer or Cancer of the Urothelium and in Healthy Participants

Inclusion: * Age \> 18 years * Meets 1 of the following criteria: * Diagnosis of renal cell carcinoma, meeting all of the following criteria: * Suitable surgical candidate * No clinical or pathologic T stage \> T2 * No clinical or pathologic evidence of vein and/or lymph node involvement * No evidence of metastatic disease as evaluated by abdominal/pelvic CT scan or MRI, chest x-ray or chest CT scan, and bone scan (if alkaline phosphatase abnormal) * Diagnosis of transitional cell carcinoma of the urothelium * Currently undergoing Bacille calmette-guérin (BCG) therapy OR has not received prior BCG therapy * Healthy participant (control) * No history of carcinoma Exclusion: * Previous or concurrent malignancy except curatively treated carcinoma in situ of the cervix or nonmelanoma skin cancer * Serious medical or psychiatric illness that would preclude study compliance * Current participation in a treatment related research study within the last 30 days * Acute illness * Bleeding disorder or dyscrasia