WithdrawnNot Applicable

Early Detection of Graft-Versus-Host Disease in Patients Undergoing a Donor Bone Marrow Transplant

Stopped: No Patients enrolled

United States0Started 2008-03

Plain-language summary

RATIONALE: Studying samples of blood in the laboratory from patients who have undergone a donor bone marrow transplant may help doctors learn more about changes that occur in DNA and identify biomarkers related to graft-versus-host disease. It may also help doctors predict how patients will respond to a donor bone marrow transplant. PURPOSE: This laboratory study is looking at early detection of graft-versus-host disease in patients undergoing a donor bone marrow transplant.

Who can participate

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

DISEASE CHARACTERISTICS: * Any patient undergoing an allogeneic bone marrow transplantation at one of the participating Mayo Clinic sites PATIENT CHARACTERISTICS: * Body weight ≥ 15 kg * Not pregnant * Not a prisoner PRIOR CONCURRENT THERAPY: * See Disease Characteristics

What they're measuring

Identification of changes in the transcriptome or proteome expression prior to clinical manifestations of graft-versus-host disease (GVHD) in patient blood samples

Timeframe: Patients beyond period of risk for developing acute GVHD

Trial details

NCT IDNCT00898612

SponsorMayo Clinic

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2012-12

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