Red Yeast Rice and Phytosterols In Statin Intolerance

Inclusion Criteria: * Men and women age \> 21 * LDL \> 100 and physician suggestion to take statin * Subject complains of muscle weakness or aching which he/she or his/her physician feels may be attributable to statin therapy * Having stopped a statin drug for personal reasons and not willing to restart this medication * Refusal to take a statin as prescribed by personal physician * CPK \< 400 * Not taking any cholesterol lowering medication, red yeast rice extract or a phytosterol product for at least 1 month prior to initiation of trial * Ability to exercise without physical restrictions * Ability to attend 12 week consecutive Change of Heart lifestyle education sessions * Liver function studies normal at baseline * Subject willing to remain off the dietary supplement CoQ10 for duration of trial * TSH must be normal Exclusion Criteria: * A history of muscle damage (CPK \> 400 IU) on statin therapy * Any active cardiac problem including chest pain, angina, shortness of breath with minimal activity, or unstable angina/acute coronary syndrome within one year * Known intolerance to one of the study drugs * Physical limitation preventing aerobic exercise program, such as severe arthritis, peripheral vascular disease, congestive heart failure, or symptom limiting pulmonary disease * Uncontrolled hypertension (defined as SBP \> 180 mmHg or DBP \> 100 mmHg * Heart attack, bypass surgery, or angioplasty/stent within 1 year of study * Triglyceride level more than 400 mg/dl * Under…