Study of Stored Tumor Samples in Young Patients With Brain Tumors

Inclusion Criteria * Tumor may be primary, progressive or recurrent CNS tumor including brain and/or spine. All tumor types will be included with a focus on medulloblastoma, HGNET, CNS embryonal tumors, gliomas, ependymoma, CPC and ATRT tumors. Low grade gliomas are currently very challenging to culture and implant but if techniques mature these will also be included. Although rare, patients with ATRT may present with a primary renal and CNS tumor. In these instances samples will be collected from both the kidney and CNS tumor for analysis if available. * Tumor may be collected at surgery prior to histologic confirmation * Age less than 40 years at the time of initial diagnosis. * Enrollment in the current version of the institution's banking protocol Exclusion Criteria * Diagnosis of tumor outside the central nervous system. * Age greater than or equal to 40 years at the time of diagnosis