Study of Metabolic Syndrome in Young Patients Who Are Acute Lymphoblastic Leukemia Survivors and … (NCT00897078) | Clinical Trial Compass
CompletedNot Applicable
Study of Metabolic Syndrome in Young Patients Who Are Acute Lymphoblastic Leukemia Survivors and Their Healthy Siblings
United States39 participantsStarted 2009-01
Plain-language summary
RATIONALE: Gathering information about metabolic syndrome from young patients who have survived acute lymphoblastic leukemia (ALL) may help doctors learn more about the disease.
PURPOSE: This phase I trial is studying the metabolic syndrome in young patients who have survived acute lymphoblastic leukemia and in healthy sibling volunteers.
Who can participate
Age range
8 Years – 21 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
DISEASE CHARACTERISTICS:
* Meets one of the following eligibility criteria:
* Childhood acute lymphoblastic leukemia survivor
* Less than 22 years old at diagnosis
* Treated from 1990-2007 at one of the following locations:
* Fred Hutchinson Cancer Research Center and/or Children's Hospital and Regional Medical Center in Seattle, WA
* Vanderbilt Children's Hospital in Nashville, TN
* Meets 1 of the following treatment criteria:
* Completed conventional therapy ≥ 11 months ago and in first complete remission
* Received an allogeneic hematopoietic cell transplantation ≥ 11 months ago and in complete remission
* No evidence of recurrent disease
* Healthy volunteer
* Full sibling of enrolled cancer survivor
* Age 8-21 (if more than 1 eligible sibling, sibling of closest age is preferred)
* No history of cancer
PATIENT CHARACTERISTICS:
* Able to speak, read, and write English
PRIOR CONCURRENT THERAPY:
* See Disease Characteristics
* No active treatment for graft-vs-host disease
Exclusion Criteria:
* Lack of ability to speak, read, and write English
* Active treatment for graft versus host disease
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Prevalence of the metabolic syndrome (MS) and its component traits in these patients and in healthy volunteers