Efficacy of Intramuscular Naloxone 0.4mg. in Prophylaxis of Intrathecal Morphine Induced Pruritus… (NCT00890942) | Clinical Trial Compass
CompletedNot Applicable
Efficacy of Intramuscular Naloxone 0.4mg. in Prophylaxis of Intrathecal Morphine Induced Pruritus After Cesarean Section
Thailand60 participantsStarted 2009-05
Plain-language summary
The purpose of this study is to determine whether intramuscular naloxone 0.4mg. is effective in prophylaxis of intrathecal morphine induced pruritus after cesarean section.
Who can participate
Age range
18 Years – 40 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* patient schedule for cesarean section ASA class 1
Exclusion Criteria:
* have contraindication for spinal block
* complicated pregnancy
* have history of drug abuse during pregnancy
* obesity BMI\>35kg./m2
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial looked at using a naloxone injection to prevent itching caused by morphine given during a C-section — is that kind of itching something I should expect with my spinal anesthesia plan, and how common is it?
2Since this study tested naloxone as a preventive measure rather than a treatment after itching starts, can you walk me through whether giving naloxone at the time of my C-section could interfere with the pain relief the morphine is supposed to provide?
3This trial is completed — do you know if the results showed that the naloxone injection was actually effective at reducing morphine-induced itching, and does that evidence influence how you manage this in your practice?
4Are there other approaches you already use to prevent or treat spinal morphine-related itching after a C-section, and how do they compare to what was tested in this study?
5If I do experience significant itching after my C-section from the morphine, what would my treatment options be at that point, and is a preventive strategy like the one in this trial something worth discussing for my specific situation?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
efficacy of intrathecal naloxone 0.4mg. in prophylaxis of intrathecal morphine induced pruritus after cesarean section