This phase II trial studies how well elesclomol sodium and paclitaxel work in treating patients with ovarian epithelial cancer, fallopian tube cancer, or primary peritoneal cancer that has returned after a period of improvement (recurrent) or is persistent. Drugs used in chemotherapy, such as elesclomol sodium and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Elesclomol sodium may also help paclitaxel work better by making tumor cells more sensitive to the drug.
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Proportion of Participants With Objective Response
Timeframe: Up to 5 years
Duration of Objective Response
Timeframe: Up to 5 years
Number of Participants Who Experienced at Least One Adverse Event
Timeframe: Up to 5 years
The Number of Participants Who Experienced at Least One Grade 3 Adverse Event
Timeframe: Up to 5 years