Functional and Physiological Responses to Lokomat Therapy (Pilot Study) (NCT00883142) | Clinical Trial Compass
CompletedNot Applicable
Functional and Physiological Responses to Lokomat Therapy (Pilot Study)
United States27 participantsStarted 2006-10
Plain-language summary
Individuals with neurological deficiencies such as those who have spinal cord injury, stroke, traumatic brain injury, Parkinson's disease, and multiple sclerosis often lose their ability to ambulate over ground. Loss of functional mobility not only impedes everyday life, but may also affect many systems and organs in the body. The investigators are interested in obtaining a wide variety of data in order to obtain a better understanding of changes that occur as a result of receiving Lokomat therapy. The investigators will be studying body composition, cardiac, pulmonary, endocrine, metabolic, and molecular changes after a 12-week clinical therapy program.
Who can participate
Age range18 Years
SexALL
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Inclusion criteria
✓. Patients will have been evaluated on the Rehabilitation Service for entry into the clinical therapy program.
✓. Any patient who is already eligible for Lokomat therapy is a candidate for this research project.
Exclusion criteria
✕. Pregnant women
✕. History of fractures of the lower extremities
✕. Bone density study indicating bone loss greater than 5 standard deviations from normal.
✕. Fixed contractures of the ankles, knees or hips
✕. Uncontrolled spasticity that significantly interferes with movement of lower extremities.
✕. Uncooperative, unmotivated patients or patients whom cannot follow instructions on a consistent basis or communicate effectively with the treating clinicians.
✕. Pressure ulcers over the greater trochanters, ischial tuberosities and sacrum.
What they're measuring
1
This pilot study for power calculations on future studies that will characterize the potential benefits of Lokomat rehabilitation training on cardiovascular function, body composition and endocrine/metabolic function
Timeframe: After completion of 24 clinical Lokomat rehabilitation sessions