WithdrawnNot Applicable

International Registry for Primary Hyperoxaluria

Stopped: Study was combined with Mayo protocol 07-003476

United States0Started 2003-09

Plain-language summary

The purpose of this study is to collect medical information from a large number of patients in many areas of the world with primary hyperoxaluria. This medical information will be entered into a registry to help the investigators compare similarities and differences in patients and their symptoms. The more patients that the investigators are able to enter into the registry, the more the investigators will be able to understand primary hyperoxaluria and learn better ways of treating patients with this disease. It is the investigators hope that by entering as many patients with PH as possible, the information that the investigators collect may help physicians diagnose patients sooner and determine what treatments may work best on patients with similar medical or genetic backgrounds.

Who can participate

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Liver biopsy or genetic analysis that confirms a diagnosis of hyperoxaluria * In the absence of a liver biopsy: * Urine oxalate excretion of \>0.8 mmol/1.73 m² /day without other causes such as enteric hyperoxaluria * Family history of PH in a sibling will be supportive * A history or current finding of kidney stones or nephrocalcinosis will be supportive * An increase in urine glycolate may suggest PHI or an increase in urine L-glycerate may suggest PHII, though not required for diagnosis. * Patients presenting in renal failure with an elevate pre-dialysis plasma oxalate of 60 umol/l and a kidney biopsy that confirms extensive oxalate deposition, or evidence of systemic oxalosis Exclusion Criteria: * Patients without any of the above or a confirmed diagnosis of PH

Trial details

NCT IDNCT00875823

SponsorMayo Clinic

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2009-07

View on ClinicalTrials.gov More Primary Hyperoxaluria trials

Plain-language summary

Who can participate

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.